In Reply: Mr Musallam and colleagues suggest that the association between microalbuminuria and VTE that we reported could have been confounded since adjustment for the presence of APS or high titers of aPLs was not performed. Antiphospholipid antibodies include lupus anticoagulants and anticardiolipin antibodies, among others. Lupus anticoagulants strongly correlate with VTE, whereas the association between anticardiolipin antibodies and VTE is disputed.1
Mahmoodi BK, Gansevoort RT, Kluin-Nelemans HC. Antiphospholipid Syndrome, Microalbuminuria, and Risk of Venous Thromboembolism—Reply. JAMA. 2009;302(9):945–946. doi:10.1001/jama.2009.1241
Customize your JAMA Network experience by selecting one or more topics from the list below.