Citing new evidence that earlier initiation of antiretroviral therapy (ART) improves survival and reduces HIV-related illnesses, the World Health Organization (WHO) said that ART should be started in all patients with HIV who have a CD4 T-cell count of 350 cells/μL or less. The agency's previous guideline revision, in 2006, called for starting treatment when a patient's CD4 count dwindled to 200 cells/μL, when symptoms of HIV disease typically emerge.
This recommendation was among several in newly revised guidelines for HIV treatment and prevention (http://www.who.int/mediacentre/news/releases/2009/world_aids_20091130/en/index.html).
Stephenson J. New HIV Recommendations. JAMA. 2010;303(3):215. doi:10.1001/jama.2009.1962
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