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July 28, 2010

Screening Newborns for Congenital Cytomegalovirus Infection

JAMA. 2010;304(4):407-408. doi:10.1001/jama.2010.1024

To the Editor: The study by Dr Boppana and colleagues1 conducted newborn screening for congenital cytomegalovirus (CMV) infection and found dried blood spots (DBS) to have a testing sensitivity of 28% to 34%. We believe that the authors' conclusion that DBS PCR assays are not suitable for screening newborns for congenital CMV infection is premature.