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August 25, 2010

Traumatic Brain Injury and Major Depressive Disorder—Reply

JAMA. 2010;304(8):857-858. doi:10.1001/jama.2010.1171

In Reply: Dr Thombs makes 3 points about our article. First, he comments that the PHQ-9 is not a clinical diagnostic interview. We agree and acknowledged this in the limitations section. We explicitly cautioned readers about comparing our results with studies that have used other diagnostic approaches. Nevertheless, others have concluded that the PHQ-9 is a valid diagnostic tool in groups with high prior probability (30%-40%) of MDD.1

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