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Lab Reports
September 1, 2010

Memory Regained

JAMA. 2010;304(9):954. doi:10.1001/jama.2010.1222

A neuroprotective chemical called P7C3 is able to restore the ability to form new memories in aging rats, according to a team led by researchers from the University of Texas Southwestern Medical Center, Dallas. The investigators showed that P7C3 stems neuronal death and cognitive decline in the animals by improving the survival of newborn neurons in the dentate gyrus within the hippocampus. This work may lead to more effective neuroprotective therapies for Alzheimer disease (Pieper AA et al. Cell. 2010;142[1]:39-51).