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Book and Media Reviews
November 24, 2010

Trust and Integrity in Biomedical Research: The Case of Financial Conflicts of Interest

JAMA. 2010;304(20):2300. doi:10.1001/jama.2010.1730

This book addresses the history, prevalence, and management of financial conflicts of interest in biomedical research, mainly in the United States. Sixteen authors array and analyze evidence and offer insight about these conflicts in 10 chapters and a preface. The editors divide the book into 3 sections. The first section describes and assesses conflicts between commercial and scientific roles in academic research, the “coevolution” of entrepreneurial academic institutions and intellectual property rights, and a “triple helix” of relationships among academe, industry, and government. The second section explains how conflicts of interest are addressed in law, journalism, and the financial services industry. One chapter in the final section summarizes current proposals to reform policy for managing conflicts of interest; the other, how contract research organizations manage such conflicts.