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News From the Centers for Disease Control and Prevention
May 21, 2014

LCMV Implicated in Illness Among Organ Transplant Recipients

Author Affiliations

Copyright American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2014;311(19):1959. doi:10.1001/jama.2014.4818

For the fifth time in the past decade, infection with lymphocytic choriomeningitis virus (LCMV) was implicated last year in a cluster of organ transplant recipients in Iowa who became ill.

Four patients had received organs or tissues from a 49-year-old man who died of an intracerebral hemorrhage. He had spent a lot of time outdoors along the Mississippi River, but investigators weren’t certain if he was exposed to rodents. Lymphocytic choriomeningitis virus is a rodent-borne virus that usually causes nonfatal, influenza-like illness and occasional aseptic meningitis. However, LCMV infection can be fatal if transmitted in utero or through organ transplantation (Schafer IJ et al. MMWR Morb Mortal Wkly Rep. 2014;63[11]:249).

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