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Clinical Trials Update
May 28, 2014

Colchicine Can Treat Full Range of Pericarditis

Author Affiliations

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2014;311(20):2056. doi:10.1001/jama.2014.5900

Low-dose colchicine should be a first-line treatment for either acute or recurrent pericarditis, report investigators of a double-blind study that randomized 240 patients with recurrent pericarditis to colchicine or placebo at 4 hospitals in northern Italy (Imazio M et al. Lancet. doi:10.1016/S0140-6736(13)62709-9 [published online March 30, 2014]). Colchicine effectively treats acute pericarditis and first recurrences, but multiple recurrences pose a major challenge in the management of pericardial diseases.