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Comment & Response
June 11, 2014

Left Atrial Fibrosis and Recurrent Arrhythmia

Author Affiliations
  • 1Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands
JAMA. 2014;311(22):2335. doi:10.1001/jama.2014.5184

To the Editor In the Delayed-Enhancement MRI Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation (DECAAF) study, Dr Marrouche and colleagues1 demonstrated that assessment of left atrial fibrosis with delayed enhancement magnetic resonance imaging (MRI) was associated with the likelihood of recurrent arrhythmia after catheter ablation for atrial fibrillation (AF). It is well recognized that the outcome of catheter ablation procedures depends on appropriate patient selection and the exact ablation strategy.2 To what extent then does the DECAAF study truly add incremental value for optimal patient selection and individualized ablation strategy?