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Comment & Response
June 11, 2014

Left Atrial Fibrosis and Recurrent Arrhythmia—Reply

Author Affiliations
  • 1Comprehensive Arrhythmia Research and Management Center, University of Utah Health Sciences, Salt Lake City
JAMA. 2014;311(22):2335-12336. doi:10.1001/jama.2014.5187

In Reply The multicenter DECAAF study showed that left atrial fibrosis quantified by MRI was the only independent predictor of ablation outcome among multiple covariates, including category of AF. This result was seen with MRI scans acquired at multiple participating centers worldwide with differing procedural approaches and ablation techniques used. Establishing a patient’s left atrial fibrosis burden offers one of the few outcome determinants that could be used in the clinic when counseling patients on whether they may benefit from ablation therapy.