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JAMA Clinical Evidence Synopsis
June 18, 2014

Exercise for Depression

Author Affiliations
  • 1Division of Psychiatry, Royal Edinburgh Hospital, United Kingdom
  • 2Institute of Child Health, University of Liverpool, United Kingdom
  • 3Centre for Clinical Brain Sciences, University of Edinburgh, United Kingdom
JAMA. 2014;311(23):2432-2433. doi:10.1001/jama.2014.4930

Clinical Question  Is exercise an effective treatment for depression?

Bottom Line  Exercise is associated with a greater reduction in depression symptoms compared with no treatment, placebo, or active control interventions, such as relaxation or meditation. However, analysis of high-quality studies alone suggests only small benefits.

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