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Comment & Response
June 25, 2014

Influence of Chronic Kidney Disease on Warfarin Therapy for Atrial Fibrillation

Author Affiliations
  • 1Section of Cardiovascular Medicine, University of Tennessee School of Medicine, Memphis
  • 2Veterans Affairs Medical Center, Memphis, Tennessee
JAMA. 2014;311(24):2542. doi:10.1001/jama.2014.5581

To the Editor Several randomized trials and meta-analyses have shown that the risk of bleeding is significantly higher for warfarin anticoagulation therapy than for treatment with aspirin.1,2 However, in the study by Dr Carrero and colleagues,3 the authors concluded that warfarin use was not associated with an increased risk of bleeding, compared with no warfarin, in patients with CKD.

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