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The World in Medicine
March 10, 1999

HIV Vaccine Trial in Africa

Author Affiliations

Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999American Medical Association

JAMA. 1999;281(10):889. doi:10.1001/jama.281.10.889

After 8 years of planning, the first clinical trial of an HIV vaccine in Africa has been launched in Uganda.

The trial is being conducted at the Joint Clinical Research Center in Kampala and at the Uganda Virus Research Institute in Entebbe. It will evaluate the safety and durability of immune response to a vaccine known as ALVAC vCP205, which is based on an attenuated canarypox virus. The vaccine contains only three HIV genes, rendering it incapable of causing HIV infection.

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