When people started to sicken and die in the 1980s from HIV/AIDS, guardians of the blood supply in many countries were slow to react. As a result, thousands of unnecessary infections followed transfusion with HIV-tainted blood products.
Today, another group of diseases that affect the blood supply is emerging—transmissible spongiform encephalopathies (TSEs). But public health leaders are flying blind on TSEs since little is known about their transmissibility through blood. The stakes are high. Some caution against do-nothing policies that could someday see thousands facing horrific deaths from these mysterious diseases. Others argue that TSEs represent at most a minuscule risk to the blood supply and that overreaction through banning of certain donors and disposal of possibly infected supplies could lead to blood shortages.
Mitka M. Will TSEs Taint the US Blood Supply?. JAMA. 1999;281(13):1157–1158. doi:10.1001/jama.281.13.1157