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Comment & Response
August 27, 2014

Cost-Related Motivations for Research

Author Affiliations
  • 1Cleveland Clinic Cole Eye Institute, Cleveland, Ohio
  • 2Department of Ophthalmology, University of Colorado–Denver, Aurora
  • 3Department of Ophthalmology, University of Pennsylvania, Philadelphia
JAMA. 2014;312(8):847. doi:10.1001/jama.2014.8354

To the Editor We agree with the authors of the Viewpoint1 on cost-related motivations for conducting research that patients should be fully informed of the purposes of a clinical trial. We were surprised, however, that the Comparison of Age-Related Macular Degeneration Treatment Trials (CATT)2 was selected as an example of a clinical trial for which cost was a primary reason for performing the trial and about which patients did not receive an adequate explanation of the purpose of the study.