Author Affiliation: Departments of Health Policy and Administration and Kinesiology, Pennsylvania State University, University Park.
Use of the dietary
supplement and androgenic steroid hormone androstenedione1
presents a number of questions and challenges. Is it a supplement or a
drug? Should youngsters be allowed to use it? Should it be sold
over-the-counter? Does it work as advertised? Is it safe?
During the past year, the public was exposed to a barrage of drug
scandals in sports. These involved Olympic champions in track and
field, swimming, and snowboarding, as well as elite cyclists, a 3-time
winner of the Boston Marathon, and a professional tennis
player.2 However, of all the drug-related stories in 1998,
none received more media attention than home run record holder Mark
McGwire's admission that he used androstenedione as a
Yesalis III CE. Medical, Legal, and Societal Implications of Androstenedione Use. JAMA. 1999;281(21):2043–2044. doi:10.1001/jama.281.21.2043