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Medical News & Perspectives
June 23/30, 1999

Lithium: Proving Its Mettle for 50 Years

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JAMA. 1999;281(24):2271-2273. doi:10.1001/jama.281.24.2271

Lexington, Ky—In 1949, Australian psychiatrist John Cade published a paper detailing the value of using lithium salts to treat acute mania. Half a century later, lithium is still used in the treatment of mood disorders, particularly bipolar illness, and ongoing research is providing evidence for other benefits of the drug, including an antisuicidal effect. To celebrate 50 years of lithium's medical usefulness, more than 300 medical professionals gathered here to discuss their lithium research.