To the Editor Dr McEvoy and colleagues1 reported a clinical trial comparing old- and new-generation depot antipsychotic medications and found no significant difference in efficacy failure for paliperidone palmitate compared with haloperidol decanoate. However, they neglected to discuss that only approximately one-third of the randomized patients completed the trial, which limits the generalizability of their findings.
Fleischhacker WW. Antipsychotic Medications for Schizophrenia. JAMA. 2014;312(14):1467–1468. doi:10.1001/jama.2014.10109
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: