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Medical News & Perspectives
October 13, 1999

Hopes for HIV Eradication Dim as Stopping HAART Allows Resurgence

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JAMA. 1999;282(14):1317-1318. doi:10.1001/jama.282.14.1317

Baltimore—A new study by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) has dealt the latest in a series of blows to the hope that it might be possible to eradicate HIV in patients treated with potent combinations of drugs known as highly active antiretroviral therapy (HAART). The group's findings, reported by NIAID director Anthony J. Fauci, MD, showed that patients whose blood (and in some cases lymph nodes) had no viable HIV after they received HAART and another drug aimed at purging hidden reservoirs of latent virus experienced a swift resurgence of HIV when they discontinued therapy.