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Contempo Updates
April 12, 2000

Effects of Mental Stress in Patients With Coronary Artery Disease: Evidence and Clinical Implications

Author Affiliations

Author Affiliations: Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, Md (Dr Krantz); Division of Cardiovascular Medicine, University of Florida, Gainesville (Dr Sheps); Department of Psychiatry, Washington University Medical Center, St Louis, Mo (Dr Carney); and the Department of Neurosciences, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark (Dr Natelson).


Contempo Updates Section Editors: Thomas C. Jefferson, MD, Contributing Editor; Stephen J. Lurie, MD, PhD, Fishbein Fellow.

JAMA. 2000;283(14):1800-1802. doi:10.1001/jama.283.14.1800

There is increasing recognition in the medical and scientific communities of the importance of behavioral and psychosocial factors in the prevention, development, and treatment of cardiovascular disorders.1 The purpose of this article is to review the evidence and mechanisms for the effects of acute and chronic stress in individuals with preexisting coronary artery disease (CAD), and evidence for the efficacy of psychosocial interventions in patients with CAD.