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August 16, 2000

Age-Related Alterations in Sleep Quality and Neuroendocrine Function: Interrelationships and Implications

Author Affiliations

Author Affiliation: Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md.

JAMA. 2000;284(7):879-881. doi:10.1001/jama.284.7.879

Normal aging is associated with a number of subjective and objective alterations in sleep quality,1,2 as well as with a variety of changes in endocrine-metabolic functions.3 To date, a precise definition of the chronology of age-related changes in sleep patterns and their possible temporal relationships with changes in neuroendocrine function has yet to be elucidated in healthy men or women. Moreover, the possible clinical and functional significance of such sleep-endocrine changes in the elderly are of great medical and societal interest, even though incompletely understood.