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December 3, 2014

Zirconium Cyclosilicate for Treatment of Hyperkalemia

Author Affiliations
  • 1Veterans Administration Medical Center, Iowa City, Iowa
  • 2Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City
JAMA. 2014;312(21):2217-2218. doi:10.1001/jama.2014.15736

Hyperkalemia is a commonly encountered clinical problem and has been reported in up to 10% of hospitalized patients, with 10% to 38% of those episodes associated with medications that block the renin-angiotensin-aldosterone system (RAAS).1 Mortality has been shown to be increased in patients with hyperkalemia even after accounting for other comorbidities.2

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