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Grand Rounds
June 6, 2001

Stroke in a Healthy 46-Year-Old Man

Author Affiliations

Author Affiliations: Cerebrovascular Division, Johns Hopkins University School of Medicine, Baltimore, Md.


Grand Rounds at The Johns Hopkins Hospital Section Editors: David B. Hellmann, MD, D. William Schlott, MD, Stephen D. Sisson, MD, The Johns Hopkins Hospital, Baltimore, Md; David S. Cooper, MD, Contributing Editor, JAMA.

JAMA. 2001;285(21):2757-2762. doi:10.1001/jama.285.21.2757

This article presents the case of a healthy 46-year-old man who experienced a dissection of the internal carotid artery. The diagnosis of this condition is not usually clear-cut, especially in a young patient with unremarkable medical history, and because of the similarity of symptoms with migraine. Often there is no obvious cause of a cerebral artery dissection, although subtle abnormalities of connective tissue may be present. Anticoagulation is generally used for therapy, but clinical trials are lacking. Carotid artery dissection should be considered as a cause of stroke in young healthy adults.