Author Affiliations: Department of Biobehavioral Health (Drs Vogler and Kozlowski) and Center for Developmental and Health Genetics (Dr Vogler), Pennsylvania State University, University Park.
Maternal smoking is a significant risk factor for low-birth-weight (LBW)
infants, which, in turn, influences infant mortality and the long-term health
outcome of surviving infants. Maternal smoking is an ideal target for intervention
and the optimal public health outcome would be prevention of all maternal
smoking. But given variability in the response to intervention attempts, a
secondary strategy is to target more effectively those individuals at highest
risk for adverse outcomes.
Vogler GP, Kozlowski LT. Differential Influence of Maternal Smoking on Infant Birth WeightGene-Environment Interaction and Targeted Intervention. JAMA. 2002;287(2):241–242. doi:10.1001/jama.287.2.241