Author Affiliation: Cardiovascular Division, Washington University School of Medicine, St Louis, Mo.
Evidence-based medicine. The concept seems so simple. Take the best
available information from clinical trials and observational studies and apply
the results in clinical practice. What in medicine could be more rational
or straightforward? Yet despite a rich evidence base for management of cardiovascular
disorders,1 study after study has demonstrated
disconcertingly low rates of compliance with widely disseminated evidence-based
treatment guidelines for managing common cardiovascular conditions including
coronary heart disease, heart failure, and hypertension.2-4
Rich MW. From Clinical Trials to Clinical Practice: Bridging the GAP. JAMA. 2002;287(10):1321–1323. doi:10.1001/jama.287.10.1321
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