[Skip to Content]
[Skip to Content Landing]
Citations 0
From the Food and Drug Administration
June 12, 2002

Synthetic Secretin Approved

Author Affiliations

Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002American Medical Association

JAMA. 2002;287(22):2936. doi:10.1001/jama.287.22.2936

The FDA has approved secretin (SecreFlo, Chesapeake Biological Laboratories, Baltimore), a synthetic formulation of the naturally occurring porcine hormone (no longer available for clinical use) for the following uses: (1) as a diagnostic test of exocrine pancreatic function. Normal response to secretin administration is volume output greater than 2.0 mL/Kg/h, and bicarbonate concentration greater than 80 mmol/L; and (2) as a test to aid in diagnosis of gastrinoma. In the absence of gastrinoma, serum gastrin levels change minimally or not at all in response to secretin.

First Page Preview View Large
First page PDF preview
First page PDF preview