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April 9, 2003

Exercise and Weight Loss in Obese Postmenopausal Women—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(14):1778. doi:10.1001/jama.289.14.1778-a

To the Editor: Dr Irwin and colleagues1 found that regular exercise resulted in reduced body weight and fat among overweight and obese postmenopausal women. We have 2 concerns about these conclusions.

First, their sample appeared to be a highly selected group, with as many as 41% having had a higher education. It is possible that their results only apply to their highly motivated sample, and not to overweight and obese postmenopausal women in general.