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April 16, 2003

Clopidogrel and Percutaneous Coronary Interventions—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(15):1925-1927. doi:10.1001/jama.289.15.1925-a

To the Editor: Dr Steinhubl and colleagues1 evaluated the effects of long-term treatment with clopidogrel and the benefit of a preprocedural loading dose in patients undergoing percutaneous coronary intervention (PCI). They reported that patients had better 1-year outcomes if they were treated with clopidogrel in addition to aspirin. I have several concerns about their study.