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Contempo Updates
Clinician's Corner
May 14, 2003

Chronic Hepatitis C Virus Infection

Author Affiliations

Author Affiliation: Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill.


Contempo Updates Section Editor: Sarah Pressman Lovinger, MD, Fishbein Fellow.

JAMA. 2003;289(18):2413-2417. doi:10.1001/jama.289.18.2413

Chronic hepatitis C virus (HCV) infection is a common worldwide problem. The infection may progress to cirrhosis with the subsequent development of complications such as ascites, encephalopathy, variceal bleeding, and hepatocellular carcinoma. Thus, early detection and therapy is of great importance. There has been substantial progress in understanding various aspects of HCV infection, including the virology, epidemiology, natural history of chronic infection, and medical therapy. The objective of this article is to provide relevant clinical information regarding the contemporary approach to patients with chronic HCV infection.