Chronic hepatitis C virus (HCV) infection is a common worldwide problem.
The infection may progress to cirrhosis with the subsequent development of
complications such as ascites, encephalopathy, variceal bleeding, and hepatocellular
carcinoma. Thus, early detection and therapy is of great importance. There
has been substantial progress in understanding various aspects of HCV infection,
including the virology, epidemiology, natural history of chronic infection,
and medical therapy. The objective of this article is to provide relevant
clinical information regarding the contemporary approach to patients with
chronic HCV infection.
Flamm SL. Chronic Hepatitis C Virus Infection. JAMA. 2003;289(18):2413–2417. doi:10.1001/jama.289.18.2413
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