Books, Journals, New Media Section Editor: Harriet
S. Meyer, MD, Contributing Editor, JAMA; David H. Morse, MS, University
of Southern California, Norris Medical Library, Journal Review Editor.
One has only to examine the list of Nobel Prize winners in Medicine
or Physiology, which might as aptly be called the Prize in Molecular Biology,
to appreciate the imbalance in support of basic science and clinical research.
Or, less grandly but very much more to the point, one might tally the National
Institutes of Health (NIH) funds going to basic scientists and to clinical
investigators. An ever-declining proportion of NIH funds go to physician researchers,
and, as the Institute of Medicine's Clinical Research Roundtable has recently
pointed out in the pages of this journal, the funding success rate of clinical
research proposals is about half that of basic science proposals. Thus, the
periodic alarm about the crisis in clinical research.
Kent D. Clinical Research. JAMA. 2003;290(7):959–961. doi:10.1001/jama.290.7.959-a
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