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Books, Journals, New Media
August 20, 2003

Clinical Research

Author Affiliations

Books, Journals, New Media Section Editor: Harriet S. Meyer, MD, Contributing Editor, JAMA; David H. Morse, MS, University of Southern California, Norris Medical Library, Journal Review Editor.

JAMA. 2003;290(7):959-961. doi:10.1001/jama.290.7.959-a

One has only to examine the list of Nobel Prize winners in Medicine or Physiology, which might as aptly be called the Prize in Molecular Biology, to appreciate the imbalance in support of basic science and clinical research. Or, less grandly but very much more to the point, one might tally the National Institutes of Health (NIH) funds going to basic scientists and to clinical investigators. An ever-declining proportion of NIH funds go to physician researchers, and, as the Institute of Medicine's Clinical Research Roundtable has recently pointed out in the pages of this journal, the funding success rate of clinical research proposals is about half that of basic science proposals. Thus, the periodic alarm about the crisis in clinical research.