Author Affiliations: Division of Nephrology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City.
Postdiarrheal Shiga toxin–mediated hemolytic uremic syndrome (HUS)
is the major cause of acute renal failure in infants and young children1 and is a substantial cause of mortality and chronic
morbidity. Adolescents who develop postdiarrheal HUS fare as well as younger
children2 but adults, especially elderly individuals,
experience a higher incidence of death and disability.3
Richard L. Siegler. Postdiarrheal Shiga Toxin–Mediated Hemolytic Uremic Syndrome. JAMA. 2003;290(10):1379–1381. doi:10.1001/jama.290.10.1379