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September 17, 2003

Early Diagnosis of Sarcoidosis—ReplyEarly Diagnosis of Sarcoidosis—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(11):1454. doi:10.1001/jama.290.11.1454-a

In Reply: In reponse to Drs Deeb and Otteson, sarcoidosis can affect every organ system and cause myriad nonspecific signs and symptoms.

The frequency of reported symptoms of sarcoidosis observed by individual practitioners appears to be strongly influenced by the patient population and type of practice. Previous reports suggest that only 1% to 4% of patients with sarcoidosis develop sinonasal involvement.1-3 The high prevalence of sinonasal symptom reported by Deeb and Otteson are much higher and serve as a reminder that there is significant variation in the rate of common and nonspecific manifestations.