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The World in Medicine
September 17, 2003

SARS Animal Reservoirs?

JAMA. 2003;290(11):1443. doi:10.1001/jama.290.11.1443-a

Scientists from England and Japan report they may have determined how powerful antimalarial drugs called artemisinins exert their killing power on the Plasmodium falciparum parasite, a finding that could aid the development of new drugs to treat malaria (Nature. 2003;424;957-961).

Artemisinins have become increasingly important as resistance to the most commonly used antimalarial medicines increases. First developed by Chinese scientists in the 1970s, these drugs' mode of action was unknown.