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November 12, 2003

Methadone Maintenance Therapy and Chronic Pain—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(18):2403. doi:10.1001/jama.290.18.2403-a

To the Editor: Dr Rosenblum and colleagues1 found that a high percentage of patients in methadone maintenance therapy programs (MMTPs) reported chronic pain.The authors pointed out that patients in MMTPs have been found to be more sensitive to pain in laboratory conditions. Their data extend this experimental finding into clinical practice, by demonstrating that patients in MMTPs complain of significantly higher levels of pain than do those in general population.