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November 19, 2003

Registering Clinical TrialsRegistering Clinical Trials

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(19):2545. doi:10.1001/jama.290.19.2545-a

To the Editor: Drs Dickersin and Rennie1 called for comprehensive registration of all randomized clinical trials. They argued that such a repository would allow reciprocal transfer of knowledge between the institutions conducting the trials and the community that actively participates in the trials or has an interest in the study outcomes. It would be a matter of open record as to which studies were not yet published. Trials that are completed, but yet unpublished, could still be included in literature reviews. This would ensure a more rigorous appraisal of all the information available on a treatment.