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November 26, 2003

Temporal Patterns of Hepatic Dysfunction and Disease Severity in Patients With SARS

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(20):2663-2665. doi:10.1001/jama.290.20.2663

To the Editor: Mildly elevated levels of aminotransferase have been reported in 23% to 50% of patients with severe acute respiratory syndrome (SARS). The clinical and pathological significance of this finding, however, remains unknown.1-3 We investigated whether liver dysfunction might reflect disease activity and have a temporal relationship with other clinical parameters in patients with SARS.