Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: We thank Dr Rosenthal for bringing
to our attention his finding that acarbose had a significant blood pressure–lowering
effect in patients with hypertension and type 2 diabetes.1 We
did not claim that we were the first to demonstrate that acarbose could reduce
hypertension. We claim that our trial is the first prospective study to find
that acarbose can decrease the risk of new cases of cardiovascular disease
and new cases of hypertension in patients with IGT.2 As
far as we know, that is still true. We also found that acarbose could reduce
both systolic and diastolic blood pressure in this group of patients, an observation
consistent with Rosenthal's observation in patients with hypertension and
Chiasson J, Josse RG, Gomis R, et al. Acarbose for Patients With Hypertension and Impaired Glucose Tolerance. JAMA. 2003;290(23):3066. doi:10.1001/jama.290.23.3066-a
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