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February 18, 2004

Plasma Concentrations of Asymmetric Dimethylarginine (ADMA) in Colombian Women With Pre-eclampsia

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(7):823-824. doi:10.1001/jama.291.7.823

To the Editor: Worldwide, pre-eclampsia is a leading cause of maternal death, affecting 3% to 5% of all pregnancies.1 Recently, elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) have been linked to pre-eclampsia and impaired endothelial function.2-5