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March 10, 2004

Optimal Control of Glycemia Among Critically Ill Patients

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(10):1198-1199. doi:10.1001/jama.291.10.1198-b

To the Editor: Based on their observational study, Dr Finney and colleagues1 speculated that less-stringent control of blood glucose levels suffices to optimize survival among critically ill patients, and that infusing more insulin may actually be harmful. In contrast, our randomized, controlled, intervention study found that intensive insulin therapy to maintain blood glucose levels below 110 mg/dL reduced mortality among critically ill patients.2

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