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March 17, 2004

Salvage Radiotherapy for Recurrent Prostate Cancer: The Earlier the Better

Author Affiliations

Author Affiliatons: Department of Radiation Oncology, Duke University Medical Center, Durham, NC.

JAMA. 2004;291(11):1380-1382. doi:10.1001/jama.291.11.1380

Adenocarcinoma of the prostate is the most commonly diagnosed malignancy in men in the United States, with 220 900 new cases and 28 900 deaths from the disease reported in 2003.1 Despite the widespread use of serum prostate-specific antigen (PSA) to screen for prostate cancer in this country, approximately 25% of men treated with radical prostatectomy for tumors presumed localized to the prostate will be found to have extension of cancer beyond the capsule of the gland.2 These men are at high risk for subsequent recurrence of their disease.