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Health Agencies Update
March 24/31, 2004

Estrogen Trial Halted

JAMA. 2004;291(12):1434. doi:10.1001/jama.291.12.1434-a

Citing concerns that women were being put at an increased risk for stroke, National Institutes of Health officials told participants in the estrogen-alone study of the Women's Health Initiative (WHI) hormone therapy trial to stop taking their pills. In addition, enough data had been compiled to conclude that estrogen alone does not seem to affect heart disease, the study's key question.

The findings also indicated that estrogen alone appears to decrease the risk of hip fracture. However, the risk of breast cancer during the study period was not affected.