To the Editor: In his Editorial about the metabolic
syndrome, Dr Grundy1 offered several possible
explanations for an apparent correlation between elevated C-reactive protein
levels and the risk of developing hypertension, a relationship of questionable
significance. This leads me to question whether the term "metabolic syndrome,"
a generic phrase for a rather specific group of physiologic impairments, makes
sense. Perhaps it would be more precise to rename this "syndrome" the "insulin
resistance/obesity complex?" Such a designation would have the advantage of
properly designating the major aspects of the disturbances as outlined by
Grundy, rather than inappropriately dignifying it with a phrase of vast content
and no specificity.
Miller AJ. Etiology of the Metabolic Syndrome. JAMA. 2004;291(12):1443. doi:10.1001/jama.291.12.1443-b