Aggressive Lipid-Lowering Therapy and Regression of Coronary Atheroma

To the Editor: In their randomized controlled trial, Dr Nissen and colleagues¹ reported that a daily dose of 80 mg of atorvastatin was associated with a greater reduction in the volume of coronary atheromas than was a daily dose of 40 mg of pravastatin. The authors concluded that their results supported aggressive cholesterol-lowering therapy.