Letters Section Editor: Robert M. Golub,
MD, Senior Editor.
To the Editor: The Women's Health Initiative
Steering Committee1 states that its findings
on the relationship between breast cancer and use of estrogen-only hormone
therapy are contrary to the preponderance of observational study results,
including those from the recent Million Women Study. However, no consideration
was given to the variation in the prevalence of obesity across study populations,
and obese women have considerably lower relative risks than thinner women
for hormone therapy–related breast cancer.2,3
Beral V, Banks E, Reeves G. Effects of Estrogen-Only Treatment in Postmenopausal Women. JAMA. 2004;292(6):683. doi:10.1001/jama.292.6.684-a
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