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August 25, 2004

Disparities in Participation in Cancer Clinical Trials

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2004;292(8):922. doi:10.1001/jama.292.8.922-a

To the Editor: Dr Murthy and colleagues1 report that cancer trial participation is low. Only 1.8% of white cancer patients enroll in therapeutic nonsurgical National Cancer Institute clinical trials. Among racial minorities, women, and elderly persons, even fewer enroll. The low inclusion rates together with an apparent selection bias for younger white people may pose a serious problem with generalizability.