Altruism and trust lie at the heart of research on human subjects. Altruistic
individuals volunteer for research because they trust that their participation
will contribute to improved health for others and that researchers will minimize
risks to participants. In return for the altruism and trust that make clinical
research possible, the research enterprise has an obligation to conduct research
ethically and to report it honestly. Honest reporting begins with revealing
the existence of all clinical studies, even those that reflect unfavorably
on a research sponsor's product.