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September 15, 2004

Clinical Trial Registration: A Statement From the International Committee of Medical Journal Editors

Author Affiliations

Author Affiliations: Dr DeAngelis is editor-in-chief, JAMA; Dr Drazen is editor-in-chief, New England Journal of Medicine; Prof Frizelle is editor, The New Zealand Medical Journal; Dr Haug is editor-in-chief, Norwegian Medical Journal; Dr Hoey is editor, CMAJ; Dr Horton is editor, The Lancet; Mr Kotzin is executive editor, MEDLINE; Dr Laine is senior deputy editor, Annals of Internal Medicine; Dr Marusic is editor, Croatian Medical Journal; Dr Overbeke is executive editor, Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine); Dr Schroeder is editor, Journal of the Danish Medical Association; Dr Sox is editor, Annals of Internal Medicine; and Dr Van Der Weyden is editor, The Medical Journal of Australia.

JAMA. 2004;292(11):1363-1364. doi:10.1001/jama.292.11.1363

Altruism and trust lie at the heart of research on human subjects. Altruistic individuals volunteer for research because they trust that their participation will contribute to improved health for others and that researchers will minimize risks to participants. In return for the altruism and trust that make clinical research possible, the research enterprise has an obligation to conduct research ethically and to report it honestly. Honest reporting begins with revealing the existence of all clinical studies, even those that reflect unfavorably on a research sponsor's product.

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