Author Affiliation: Department of Neurology,
Beth Israel Deaconess Medical Center, Boston, Mass.
In 1998, I wrote an editorial entitled “Stroke Treatment: Promising
but Still Struggling”1 in an issue of JAMA that featured 5 articles on stroke. In that issue,2 2 articles concerned carotid artery surgery, one article
reported the results of a trial of acute stroke patients receiving treatment
with a heparinoid, another focused on anticoagulation in atrial fibrillation,
and the fifth reviewed thrombolytic and neuroprotective treatments—each
in their early years of application. During the past 6 years, there have been
dramatic improvements in the technology available to diagnose stroke, and
more studies have reported the results of thrombolytic therapy. This issue
of JAMA includes one article on stroke diagnosis3 and 3 articles on outcomes following thrombolytic
treatment with alteplase for patients with acute ischemic stroke.4-6 As these articles suggest,
while there has been some progress, stroke treatment is still struggling and
has a long way to go.
Caplan LR. Treatment of Acute Stroke: Still Struggling. JAMA. 2004;292(15):1883–1885. doi:10.1001/jama.292.15.1883
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