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October 20, 2004

Tuberculosis: A Call for Papers

Author Affiliations

Author Affiliations: Dr DeAngelis is Editor-in-Chief and Ms Flanagin is Managing Senior Editor, JAMA .

JAMA. 2004;292(15):1889. doi:10.1001/jama.292.15.1889

Tuberculosis (TB) has been infecting and killing humans for more than 3000 years.1 Despite the many advances of modern medicine, TB remains one of the world’s leading infectious causes of death. Currently one third of the world’s population is infected with the TB bacillus and approximately 2 million individuals die each year of TB,2 with more than 90% of infections and deaths occurring in low- and middle-income countries.3 In 2000, an estimated 8.7 million new cases of TB were reported, and approximately 2% to 3% were multidrug-resistant.4 In addition, TB is the leading cause of morbidity and mortality among individuals infected with the human immunodeficiency virus (HIV),2 who have a greater risk of developing the disease.5