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October 27, 2004

Acid Suppression and Pneumonia: A Clinical Indication for Rational Prescribing

Author Affiliations

Author Affiliation: Departments of Medicine and Epidemiology & Biostatistics, University of Western Ontario, London, Ontario.

JAMA. 2004;292(16):2012-2013. doi:10.1001/jama.292.16.2012

Disorders of the upper gastrointestinal (GI) tract, both symptomatic and asymptomatic, have been ubiquitous in humans throughout the history of medicine. Although important advances, such as the discovery of Helicobacter pylori, have offered curative options for many patients, lifestyle habits and the increasing use of other medication classes, including nonsteroidal anti-inflammatory drugs (NSAIDs) and anticoagulants in western countries, ensure that disorders such as gastroesophageal reflux and NSAID gastropathy will remain prevalent for decades to come.