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Medical News & Perspectives
December 8, 2004

Scientists Probe Aldosterone’s Role in Hypertension and Heart Disease

JAMA. 2004;292(22):2704-2707. doi:10.1001/jama.292.22.2704

Chicago—A hormone once believed to be a mediator of the body’s electrolyte and water balance is now being appreciated by researchers as a potentially powerful therapeutic actor in a variety of medical conditions.

Findings emerging from studies aimed at dissecting aldosterone’s role in human physiology are encouraging scientists to explore whether therapeutic actions against aldosterone can benefit patients with hypertension, ischemic heart disease, stroke, heart failure, and renal disease.